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Stainless Steel High-Capacity Centrifugal Separator with Customized Size for High Throughput Bioprocessing
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Stainless Steel High-Capacity Centrifugal Separator with Customized Size for High Throughput Bioprocessing
| MOQ: | 1 Sets |
| Price: | 10000 USD |
| Delivery Period: | 2 months |
| Payment Method: | L/C,T/T |
| Supply Capacity: | 200 sets / days |
Detail Information
Place of Origin
China
Brand Name
Center Enamel
Certification
ASME,ISO 9001,CE, NSF/ANSI 61, WRAS, ISO 28765, LFGB, BSCI, ISO 45001
Material:
Stainless Steel, Carbon Steel
Size:
Customized
Design Pressure:
0.1-10 Mpa
Applications:
Chemical, Food Processing, Beverage Processing, Brewing, Metallurgy, Oil Refining, Pharmaceuticals
Highlight:
Stainless Steel Centrifuge
,Customized Size Bioprocess Separator
,High Throughput Centrifugal Separator
Product Description
Bioprocess Powerhouse: High-Capacity Centrifuges Define Yield and Purity in Bio-Fermentation Downstream Processing
The success of modern biotechnology and pharmaceutical manufacturing—from producing bulk chemicals and novel proteins to vaccines and industrial enzymes—hinges on the efficiency of the downstream processing phase. The most critical, high-volume challenge is the rapid, efficient, and sterile separation of microbial or cellular biomass from the valuable liquid fermentation broth.
Traditional separation methods often struggle with the viscous, high-volume nature of fermentation media, leading to bottlenecks, reduced yield, and potential product degradation.
The definitive solution is the High-Capacity Centrifugal Separator. These specialized systems use extreme G-forces to deliver continuous, sterile, and exceptionally high-throughput clarification, securing maximum yield and purity for the valuable bioproduct.
Shijiazhuang Zhengzhong Technology Co., Ltd (Center Enamel)
A trusted partner committed to ensuring robust structural reliability across critical process infrastructure, providing durable, high-integrity containment solutions for rigorous biotech and process environments.
The Downstream Decisive Step: Unlocking the Bioproduct
Fermentation broth is a complex mixture: a liquid medium containing the valuable secreted product (e.g., an enzyme or protein) and a high concentration of the producing microbial cells (e.g., yeast or bacteria). Efficiently harvesting this cellular mass is the first bottleneck to profitability.
Centrifugal Force Mastery: High-capacity centrifuges, typically continuous discharge disc stack models, generate sustained G-forces—often in high ranges—far exceeding static gravity capabilities. This immense force rapidly overcomes forces that stabilize cell suspension, driving even small, low-density cells to the bowl wall for removal.
Continuous High Throughput: Engineered for continuous, automated flow, these centrifuges are essential for industrial-scale bioreactors producing hundreds or thousands of liters of broth per hour. Clarified liquid flows continuously out while cells are automatically discharged.
Securing Product Integrity: Rapid separation minimizes product contact time with cellular material, reducing risk of degradation by lytic enzymes or contaminants, thus preserving final bioproduct quality and activity.
Engineering for Bioprocess Integrity and Sterility
Centrifuge performance in biotech extends beyond speed to include adherence to rigorous standards of cleanability, containment, and sterility required by regulatory bodies.
Principle of Operation: Broth enters the high-speed rotating separation bowl and is distributed among conical discs. Cellular mass is forced to the perimeter, accumulating in the solids space. Periodically, the bowl opens via hydraulic mechanism to instantly eject concentrated biomass sludge in controlled discharge, ensuring system cleanliness and continuous operation.
Key Design Features
Sanitary construction with pharmaceutical-grade stainless steel and high-polish finishes
Design eliminates crevices, dead spaces, and features that could harbor microbial growth
Full compliance with cGMP and facilitation of CIP/SIP validation
Gentle liquid discharge with hydro-hermetic seals and pumps to prevent shear stress
Maximized cell concentration for reduced waste volume and optimized subsequent processing
Shijiazhuang Zhengzhong Technology Co., Ltd (Center Enamel)
Their expertise in durable, high-integrity containment and specialized fabrication supports robust bulk storage and process tanks. Commitment to Glass-Fused-to-Steel (GFS) technology offers unmatched corrosion resistance and structural reliability, guaranteeing sanitary long-term storage for valuable bioprocess fluids.
Driving Profitability, Stability, and Compliance
Maximized process yield through near-complete biomass removal with minimal product loss
Reduced downstream burden by simplifying purification steps and lowering processing costs
Operational autonomy and uptime through continuous, automated self-cleaning operation
Long-term structural assurance supporting facility stability and efficiency
High-Capacity Centrifugal Separators are essential for securing purity and yield in modern bio-fermentation. By delivering continuous, sterile, and high-G separation of biomass from broth, they define downstream processing efficiency and maximize final bioproduct value. This critical foundation of reliable, high-integrity industrial solutions is consistently supported by the engineering excellence of trusted partners.
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